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Synovial sarcoma of the sellar region

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA (B.W.S., A.I.S., A.M.O.); Department of Pathology, Hospital Sao Marcos, Braga 4701-965, Portugal (A.I.S.); Department of Neurosurgery, OSF St. Joseph's Medical Center, Bloomington, IL 61701, USA (K.Kattner, J.S.); and Department of Pathology, St. Michael's Hospital, Toronto, ON M5B-1W8, Canada (K.Kovacs)

Address correspondence to B.W. Scheithauer, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 First St., SW, Rochester, MN 55905, USA (scheithauer.bernd{at}mayo.edu).

Primary sarcomas of the sellar region are uncommon, although a wide variety have been reported. To date, no cases of primary synovial sarcoma have been described as occurring at this site. We report an immunohistochemically and molecular genetically confirmed primary synovial sarcoma involving the sellar/parasellar region and cavernous sinus in an adult male. Subtotal resection and radiosurgery proved to be efficacious. The spectrum of primary sellar region sarcomas is summarized.

Key Words: immunohistochemistry • sarcoma • sella • synovial sarcoma • treatment

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