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First published on August 17, 2007
A more recent version of this article appeared on October 1, 2007
Neuro Oncol 2007, DOI:10.1215/15228517-2007-029
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© Copyright 2007 by the Society for Neuro-Oncology

Received September 28, 2006
Accepted November 28, 2006

Case Studies

Synovial sarcoma of the sellar region

Bernd W. Scheithauer 1*, Ana Isabel Silva 2, Keith Kattner 3, Jason Seibly 3, Andre M. Oliveira 1, Kalman Kovacs 4

1 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
2 Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA, and Department of Pathology, Hospital Sao Marcos, Braga 4701-965, Portugal
3 Department of Neurosurgery, OSF St. Joseph's Medical Center, Bloomington, IL 61701, USA
4 Department of Pathology, St. Michael's Hospital, Toronto, ON M5B-1W8, Canada

* To whom correspondence should be addressed. E-mail: scheithauer.bernd{at}mayo.edu.


   Abstract

Primary sarcomas of the sellar region are uncommon, although a wide variety have been reported. To date, no cases of primary synovial sarcoma have been described as occurring at this site. We report an immunohistochemically and molecular genetically confirmed primary synovial sarcoma involving the sellar/parasellar region and cavernous sinus in an adult male. Subtotal resection and radiosurgery proved to be efficacious. The spectrum of primary sellar region sarcomas is summarized.

Key Words: immunohistochemistry, sarcoma, sella, synovial sarcoma, treatment


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Copyright 2007 by Society for Neuro-Oncology