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Neuropathology |
Departments of Neurosurgery (L.E., M.N.P.), Neuropathology (Ö.K.-Y., A.S.), and Radiology (G.E.), Marmara University School of Medicine, Istanbul, Turkey; Department of Anatomy, Universitario de Santiago de Compostela, Lugo, Spain (S.V.); Department of Laboratory Medicine, St. Michael's Hospital, Toronto, Ontario, Canada (K.K.); and the Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN 55905 (B.W.S.)
1 Address correspondence and reprint requests to B. W. Scheithauer, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1st St. SW, Rochester, MN 55905.
Abstract
We report a case of suprasellar papillary craniopharyngioma metastatic to the temporoparietal region 2 years after its initial resection. The literature documents examples of craniopharyngioma recurrences along the surgical tract, as well as remote ipsi- and contralateral metastases via cerebrospinal fluid seeding. Ours is the second report of a craniopharyngioma of papillary type to exhibit metastatic behavior. The tumor spread opposite the side of craniotomy. Although a rare occurrence, it confirms the limited capacity of histologically benign craniopharyngiomas to undergo meningeal seeding, likely the result of surgical manipulation. Immunohistochemical demonstration of increased microvascular density and vascular endothelial growth factor expression, as well as a high vascular endothelial growth receptor (VEGFR2) signal by in situ hybridization, suggests that tumor vascularity facilitated angiogenesis and may have been involved in the establishment and growth of the metastatic deposit.
References
Adamson, T.E., Wiestler, O.D., Kleihues, P., and Yasargil, M.G. (1990) Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J. Neurosurg. 73, 12-17.[Medline]
Barloon, T.J., Yuh, W.T.C., Sato, Y., and Sickels, W.J. (1988) Frontal lobe implantation of craniopharyngioma by reported needle aspirations. AJNR Am. J. Neuroradiol. 9, 406-407.[Medline]
Burger, P.C., and Scheithauer, B.W. (1994) Tumors of the Central Nervous System. Atlas of Tumor Pathology, third series, fascicle 10. Washington DC: Armed Forces Institute of Pathology. pp. 349-354.
Cooper, P.R., and Ransohoff, J. (1972) Craniopharyngioma originating in the shenoid bone: Case report. J. Neurosurg. 36,102 -106.[Medline]
Crotty, T.B., Scheithauer, B.W., Young, W.F., Jr., Davis, D.H., Shaw, E.G., Miller, G.M., and Burger, P.C. (1995) Papillary craniopharyngioma: A clinicopathological study of 48 cases. J. Neurosurg. 83,206 -214.[Medline]
Demaerel, P., Moseley, I.F., and Scaravilli, F. (1993) Recurrent craniopharyngioma invading the orbit, cavernous sinus and skull base: A case report. Neuroradiology 35,261 -263.[CrossRef][Medline]
Duff, J.M., Meyer, F.B., Ilstrup, D.M., Laws, E.R., Jr., Schleck, C.D., and Scheithauer, B.W. (2000) Long term outcomes for surgically resected craniopharyngiomas. Neurosurgery 46,291 -302.[CrossRef][ISI][Medline]
Duff, T.A., and Levine, R. (1983) Intrachiasmatic craniopharyngioma: Case report. J. Neurosurg. 59,176 -178.[Medline]
Eldevik, O.P., Blaivas, M., Gabrielsen, T.O., Hald, J.K., and Chandler, W.F. (1996) Craniopharyngioma: Radiologic and histologic findings and recurrence. AJNR Am. J. Neuroradiol. 17,1427 -1439.[Abstract]
Ferrara, N. (2000) Vascular endothelial growth factor and the regulation of angiogenesis. Recent Prog. Horm. Res. 55,15 -35.
Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1, 27-31.[CrossRef][ISI][Medline]
Folkman,J., and Sing, Y. (1992)
Angiogenesis.J. Biol. Chem.
267,10931
-10934.
Gökalp, H.Z., Egemen, N., Ildan, F., and Bacaci, K. (1991) Craniopharyngioma of the posterior fossa. Neurosurgery 29,446 -448.[Medline]
Gupta, K., Kuhn, M.J., Shevlin, D.W., and Wacaser, L.E.
(1999) Metastatic craniopharyngioma. AJNR Am. J.
Neuroradiol. 20,1059
-1060.
Honnegger, J., Renner, C., Fahsbusch, R., and Adams, E.F. (1997) Progesterone receptor gene expression in craniopharyngiomas and evidence for biological activity. Neurosurgery 41,1359 -1363.[CrossRef][Medline]
Israel, Z.H., and Pomeranz, S. (1995) Intracranial craniopharyngioma seeding following radical resection. Pediatr. Neurosurg. 22,210 -213.[Medline]
Ito, M., Jamshidi, J., and Yamanaka,K. (2001) Does craniopharyngioma metastasize? Case report and review of the literature. Neurosurgery 48,933 -935.[CrossRef][Medline]
Kahn, E.A., Gosch, H.H., Seeger, J.F., and Hicks, S.P. (1973) Forty-five years experience with the craniopharyngiomas. Surg. Neurol. 1,5 -12.[Medline]
Katoh, R., Miyagi, E., Kawoi, A., Hemmi A., Komiyama A., Oyama T., and Shibuya M. (1999) Expression of vascular endothelial growth factor (VEGF) in human thyroid neoplasms. Hum. Pathol. 30,891 -897.[CrossRef][Medline]
Lee, J.H., Kim, C.Y., Kim, D.G., and Jung, H.W. (1999) Postoperative ectopic seeding of craniopharyngioma: Case illustration. J. Neurosurg. 90,796 .[Medline]
Lloyd, R.V., Scheithauer, B.W., Kuroki, T., Vidal S., Kovacs K., and Stefaneanu L. (1999) Vascular endothelial growth factor (VEGF) expression in human pituitary adenomas and carcinomas. Endocr. Pathol. 10,229 -235.[ISI][Medline]
Majlessi, H., Shariat, A.S., and Katirai, A. (1978) Nasopharyngeal craniopharyngioma: Case report. J. Neurosurg. 49,119 -120.[Medline]
Malik, J.M., Cosgrove, G.R., and VandenBerg, S.R. (1992) Remote recurrence of craniopharyngioma in the epidural space: Case report. J. Neurosurg. 77,804 -807.[Medline]
Nelson, G.A., Bastian, F.O., Schlitt, M., and White, R.L. (1988) Malignant transformation in craniopharyngioma. Neurosurgery 22,427 -429.[Medline]
Nishi, T., Kuratsu, J., Takeshima, H., Saito, Y., Kochi, M., and Ushio, Y. (1999) Prognostic significance of the MIB-1 labeling index for patient with craniopharyngioma. Int. J. Mol. Med. 3,157 -161.[Medline]
Petito, C.K. (1996) Craniopharyngioma: Prognostic importance of histologic features. AJNR Am. J. Neuroradiol. 17,1441 -1442.[Medline]
Petito, C.K., DeGirolami, U., and Earle, K.M. (1976) Craniopharyngiomas: A clinical and pathological review. Cancer 37,1944 -1952.[CrossRef][Medline]
Qian, X., Bauer, R.A., Xu, H.S., and Lloyd, R.V. (2001) In situ hybridization detection of calcitonin mRNA in routinely fixed, paraffin-embedded tissue sections: A comparison of different types of probes combined with tyramide signal amplification. Appl. Immunohistochem. Mol. Morphol. 9,61 -69.[ISI][Medline]
Raghavan, R., Dickey, W.T., Jr., Margraf, L.R., White, C.L., III, Coimbra, C., Hynan, L.S., and Rushing, E.J. (2000) Proliferative activity in craniopharyngiomas: Clinicopathological correlations in adults and children. Surg. Neurol. 54,241 -247.[CrossRef][Medline]
Ragoowansi, A.T., and Piepgras, D.G. (1991) Postoperative ectopic craniopharyngioma: Case report. J. Neurosurg. 74,653 -655.[Medline]
Solarski, A., Panke, E.S., and Panke, T.W. (1978) Craniopharyngioma in the pineal gland. Arch. Pathol. Lab. Med. 102,490 -491.
Sorva, R., Jaaskinen, J., and Heiskanen, O. (1987) Craniopharyngioma in children and adults: Correlations between radiological and clinical manifestations. Acta Neurochir. (Wien) 89, 3-9.[Medline]
Thapar, K., Stefaneanu, L., Kovacs, K., Scheithauer, B.W., Lloyd, R.V., Muller, P.J., and Laws, E.R. (1994) Estrogen receptor gene expression in craniopharyngiomas: An in situ hybridization study. Neurosurgery 35,1012 -1017.[Medline]
Vaquero, J., Zurita, M., de Oya, S., Coca S., Morales C., and Salas C. (1999) Expression of vascular permeability factor in craniopharyngioma. J. Neurosurg. 91,831 -834.[Medline]
Vidal, S., Kovacs, K., Horvath, E., Scheithauer, B.W., Kuroki, T., and Lloyd, R.V. (2001) Microvessel density in pituitary adenomas and carcinomas. Virchows Arch. 438,595 -602.[CrossRef][ISI][Medline]
Vidal, S., Kovacs, K., Lloyd, R.V., Meyer, P.B., and Scheithauer, B.W. (2002) Angiogenesis in craniopharyngiomas: Relationship to treatment and outcome. Cancer (In Press).
Weiner, H.L.,Wisoff, J.H., Rosenberg, M.E., Kupersmith, M.J., Cohen, H., Zagzag, D., Shiminski-Maher, T., Flamm, E.S., Epstein, F.J., and Miller, D.C. (1994) Craniopharyngiomas: A clinicopathological analysis of factors predictive of recurrence and functional outcome. Neurosurgery 35,1001 -1010.[Medline]
Yasargil, M.G., Curcic, M., Kis, M., Siegenthaler, G., Teddy, P.J., and Roth, P. (1990) Total removal of craniopharyngiomas: Approaches and long-term results in 144 patients. J. Neurosurg. 73,3 -11.[Medline]
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