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Neuro Oncol 1999 1(4):289-291; DOI:10.1215/15228517-1-4-289
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Duke University Press

Case Study

Obstructive sleep apnea syndrome in a patient with medulloblastoma

Glen Greenough1, Michael Sateia and Camilo E. Fadul

Sleep Disorders Center, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756

1 Address correspondence and reprint requests to Glen Greenough, M.D., Sleep Disorders Center, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756.

Abstract

We present one adult patient with medulloblastoma who developed polysomnographically documented obstructive sleep apnea after posterior fossa surgery. The sleep apnea worsened in conjunction with clinical and imaging-con-firmed neoplastic progression and clinically improved after craniospinal radiation therapy. Medulloblastoma or its surgical treatment has never before been implicated in a sleep-related breathing disorder. We discuss possible mechanisms for its occurrence and management implications.

References

Adelman, S., Dinner, D.S., Goren, H., Little, J., and Nickerson, P. (1984) Obstructive sleep apnea in association with posterior fossa neurologic disease. Arch. Neurol. 41,509 -510.[Abstract]

Auer, R.N., Rowlands, C.G., Perry, S.F., and Remmers, J.E. (1996) Multiple sclerosis with medullary plaques and fatal sleep apnea (Ondine's curse). Clin. Neuropathol. 15,101 -105.[ISI][Medline]

Garcia-Rio, F., Prados, C., Racionero, M.A., Soledad, S., Pino, J.M., and Villamor, J. (1997) Nocturnal arterial oxygen desaturation secondary to a sphenoidal meningioma. Respiration 64,229 -232.[Medline]

Ito, K., Murofushi, T., Mizuno, M., and Semba, T. (1996) Pediatric brain stem gliomas with the predominant symptom of sleep apnea. Int. J. Pediatr. Otorhinolaryngol. 37, 53-64.[CrossRef][ISI][Medline]

Sadaoka, T., Kakitsuba, N., Fujiwara, Y., Kanai, R., and Takahashi, H. (1996) Sleep-related breathing disorders in patients with multiple system atrophy and vocal fold palsy. Sleep 19,479 -484.[ISI][Medline]

Salazar-Grueso, E.F., Rosenberg, R.S., and Roos, R.P. (1988) Sleep apnea in olivopontocerebellar degeneration: Treatment with trazodone. Ann. Neurol. 23,399 -401.[CrossRef][Medline]

Sheridan, F., Scharf, D., Henderson, V.W., and Miller, C.A. (1990) Lipomas of the mesancephalic tectum and rostral pons associated with sleep apnea syndrome. Clin. Neuropathol. 9,152 -156.[Medline]





This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
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Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Greenough, G.
Right arrow Articles by Fadul, C. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation


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Copyright 1999 by Society for Neuro-Oncology