QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:
Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via ISI Web of Science (1) Citing Articles via Google Scholar Google Scholar Articles by Chang, S. M. Articles by Bigner, D. D. Search for Related Content PubMed PubMed Citation

GNOSIS: Guidelines for neuro-oncology: Standards for investigational studies—reporting of phase 1 and phase 2 clinical trials

Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA (S.M.C., S.L.R, N.B., K.R.L.; Department of Oncology, Mayo Clinic Cancer Center; Rochester, MN 55905, USA (J.C.B.); National Cancer Research Network, Leeds LS16 6QB, UK (R.S.K.); Comprehensive Cancer Center, Duke University Medical Center, Durham, NC 27710, USA (D.D.B.)

¹ Address correspondence to Susan M. Chang, Department of Neurological Surgery, University of California San Francisco, 400 Parnassus Ave., A 808, Box 0372, San Francisco, CA 94143-0372. (changs{at}neurosurg.ucsf.edu).

Abstract

We present guidelines to standardize the reporting of phase 1 and phase 2 neuro-oncology trials. The guidelines are also intended to assist with accurate interpretation of results from these trials, to facilitate the peer-review process, and to expedite the publication of important and accurate manuscripts. Our guidelines are summarized in a checklist format that can be used as a framework from which to construct a phase 1 or 2 clinical trial.