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Treatment of progressive metastatic glomus jugulare tumor (paraganglioma) with gemcitabine

Dartmouth-Hitchcock Medical Center/Norris Cotton Cancer Center, Lebanon, NH 03756 (J.M.P.); and Phoebe Putney Memorial Hospital/Phoebe Cancer Center, Albany, GA 31701 (R.F.K.)

¹ Address correspondence and reprint requests to Marc Pipas, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756.

Abstract

Paragangliomas are rare tumors of the paraganglia composed of specialized neural crest cells arising in association with sympathetic ganglia. Here we report a case of progressive, metastatic paraganglioma (glomus jugulare tumor) responsive to single agent gemcitabine. In addition, a brief review of chemotherapy for paraganglioma follows the case presentation.

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